Drayton and EPH both do a thermostat designed for use with a zoned system, Drayton with a TRV's and wall thermostat on/off and EPH with OpenTherm with thermostats set as master/slave.
But most gas central heating boilers are designed to modulate and although they will work with a zoned system they will not work efficiently.
Hive have an unusual approach, you have a single wall thermostat which connects to TRV's wireless and the TRV's send a demand for heat, there is nothing to stop you connecting 20 Hive thermostats in parallel so any one will fire the boiler, but with zone valves, the thermostat does not connect to boiler, but to the zone valve, and the zone valve in turn connects to boiler, so boiler only fires up after the valve has opened.
So the question is how much control do you want? If you want room by room control may as well latch the zone valves open or remove them or link together, they don't have a job to do any more, you can use the TRV heads, but if your OK with a group of rooms together then keep the zone valves.
I looked at Hive, it seemed rather expensive, the wall thermostat was cheap enough, but the TRV heads are on the expensive side, I have 9 electronic TRV heads, 4 brought from last house Energenie at around £76 per pair, and 5 eQ-3 which are only blue tooth at £15, the non blue tooth down to £10 each. I use Nest not Hive.
So you need to decide what compromise you want, yes could use all Hive TRV's but they are not cheap, I used the expensive TRV's down stairs, and cheap upstairs and kitchen, the cheap has open window detection which also detects an open door, so auto turns off heat in kitchen when unloading the car.
So combining the two zone valves together and loads of programmable TRV heads is best, but expensive, but you only need one Hive wall thermostat, continuing with zones, cheaper but need a second Hive wall thermostat. Well say cheaper depends how many TRV heads you need.