firstly should follow manufacturers instructions, they are not there for fun.
flashing up and defaulting the panel with wireless will create its own issues, you may find that if you didn't back up the config with radio devices that you have to learn them all back on and re do commissioning mode, always wise to recomission and check devices after a flash upgrade.
my biggest concern is updates of wireless expanders takes please when new devices are added and you may find that if the wireless expanders are not uptodate that new wireless devices don't work so well.