You would need to know the make and model to figure out the vent size you need but assume that it would be 100cm2( about a 5 inch core drill usually works) as to high or low, it doesn't matter as long as you don't block it up .
steph
Could be a leak on the heat exchanger, I had to change one about 3 months ago for the same reason, ie no visible leaks on the rads or pipework. Just an idea mind you.
steph