How many tyres are 205/75-16 ? (ilegal to mix sizes on a axle)
What van ? Does is require a class 5 or 7 MOT (class 7 checks load ratings - wrong rating and you fail)
Is it taxed PLG ? - get stopped with wrong tyres by DVLA for over weight for the tyres and walk home with a GV9 !
The load/speed ratings are different for the 2 sizes, also both come in 8 & 10ply ratings.
Size wise it DOES matter, 205/75-16's are a smaller diameter AND width (regardless of how small the difference is) - when your speedo is showing 70 on the motorway you'll be using 70mph worth of fuel, 70mph worth of wear & tear but only actually traveling @ 65 !