Shingles vaccine for our older members

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I asked for it because someone in my family got Shingles in retirement, and it is a troublesome, painful disease.

There seems to be an unexpected benefit.

"In 2013, Wales rolled out Zostavax to those aged 70-79 on September 1. The cut-off meant that anyone turning 80 after that date could get jabbed but everyone older, even by one day, never became eligible.

As Geldsetzer puts it, that policy created “these beautiful comparison groups. If you take 1,000 people born one week, and compare them to 1,000 people born a week later, there shouldn’t be anything [systematically] different between them except for their probability of getting the shingles vaccine.”

The two groups in Wales, comprising over 280,000 people, did show a striking difference over the next seven years: the vaccine-eligible group were 20 per cent less likely to receive a dementia diagnosis. Eric Topol, a US researcher who writes the Ground Truths medical blog, surveyed the evidence and concluded recently: “If this vaccine was a drug and reduced Alzheimer’s by 20 per cent, it would be considered a major breakthrough.”

FT.com

Much more info available.

Hooray for the NHS and its data collection. Drug companies should be paying billions for access.

 
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"Research from 2024 showed that the newer Shingrix vaccine and RSV vaccine are both linked to an even greater reduction of dementia risk, attributed to an immune-boosting ingredient. One theory is that the vaccines somehow reduce inflammation, which might otherwise prime brain cells to go rogue or reactivate viruses. It is unclear, though, how these findings relate to people who have already had shingles, nor whether a jab would lower their dementia risk."
 
"Over the past year, data from separate vaccine rollouts in Wales, Australia, Canada and the US suggests it can delay the onset of dementia, slow down its progress and cut the risk of death among those already diagnosed. Despite the vaccine being aimed at the over-50s, the 39-year-old researcher leading some of the analyses is so convinced by the data that he has had the jab himself."
 
Shingrix is two doses. Usually these are given between 6 and 12 months apart.

I think it can be done more quickly for some people, especially younger people who need it.


If you are not eligible for the free NHS jab, you can pay for it, for example at some Boots pharmacies.
 
"The unexplained connection between shingles vaccination and lowered dementia risk matters for several reasons: it highlights the power of “natural studies”, which harness mass observational data; it shows how repurposing vaccines and therapies can offer hope where novel offerings are falling short; it implicates viruses in neurodegenerative diseases; and it reveals the potential wider gains of vaccination at a time when public confidence is wobbling."

I wonder if it explains why so many antivaxxers are barmy.
 
I wonder if it explains why so many antivaxxers are barmy.
Are you talking about those who refuse all jabs or those who pick and choose?

I think when I reach the appropriate age, on the balance of evidence I'd have the shingles one...

Not so the myriad of covid/flu jabs as I've had none of them and not contracted either disease as far as I'm aware of...

So there is indeed a difference between properly researched vaccinations and the 'let's hope it works' ones!
 
Not so the myriad of covid/flu jabs as I've had none of them and not contracted either disease as far as I'm aware of...
A bit like saying my granny smoked all of her life and never got any smoking related diseases. The majority of people who get vaccinated may not need it but it is an insurance policy incase you do, then you would be glad you got vaccinated rather than wishing that you had.
 
A bit like saying my granny smoked all of her life and never got any smoking related diseases. The majority of people who get vaccinated may not need it but it is an insurance policy incase you do, then you would be glad you got vaccinated rather than wishing that you had.
Unless of course if your 'insurance policy' has side effects and the small print has a get out clause for the manufacturer...

Best to wise up in the first place and choose carefully ;)
 
Unless of course if your 'insurance policy' has side effects and the small print has a get out clause for the manufacturer...

Best to wise up in the first place and choose carefully ;)
Myy choice is what medical Drs decide is best, right or wrong they are more qualified than I am to make life and death decisions.
 
How's your leg. Did you go to work.
Yes but they wont let me do call outs through the night as they think it is best to rest it with just my 37 core hours. Annoyed that I told them but that is what you get for being honest.
 
Myy choice is what medical Drs decide is best, right or wrong they are more qualified than I am to make life and death decisions.
But you have to also trust your own instincts...

At the end of the day it's your body and you should know it best!
 
Never having a typhoid vax again, after it put me in bed for a week. So does that make me an antivaxer
 
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