They normally fail because of their location and debris falling into mechanism or a loose connection!
But frequent switching of a load is also a factor in why they fail. There is good reason for them being described as an isolator and not as a switch.
I cannot find quoted life times for isolators ( can't be bothered to spend time looking )
but as an example this is the quoted lifetime of a MK switch ( Logic Plus™ plateswitches that comply with BS EN 60669-1: 1999
Operational testing (all plateswitches ):
tested to 100,000 operations for mechanical life
tested to 40,000 operations at 10 amp rating
tested to 10,000 operations at 20 amp rating