This is the best way Jim,
Trim a couple of inches of the old plaster from all around the hole where the air vent was. This gives you an even plane all around the hole. Get the two bricks ready, and mix a little sand and cement mortar/plasticiser. Give the hole/square a clean/wet down all around using a wet brush (not overwet). Bed the bricks into the mortar, keeping the face of the bricks level with the "original brick" surface. Let it set, then the following day, coat the patch out to within a ml or two of the "existing plaster", using mortar/render, or bonding coat/undercoat plaster, if you have some. Finish the patch out to flush with multi finish when backing coat has set.
Roughcaster.