Curtain rails and the odd fixing do often get the 3" screw treatment, with a single plug knocked in deep together with a good squidge of gripfill to fill any cavity to prevent long term plasterboard collapse and sagging curtain rails.
Rigifix are the dogs *******s for kitchen cupboards and radiators, anything thats heavy and can hide some big fixings. Once you've used them you won't mind the price quite so much.
Yes I do sometimes. For kitchen cabinets I cut a section of PB out and fixed a floor board to the wall first. If accuracy is important, IT'S more accurate screwing into plywood than using wallplugs.
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