trust you have flushed the heating system bdog. this sometimes happens when you only have one or two rads on, and the rest off. try turning the lockshield down a bit with heating running, see if this makes any difference, good luck.
Don't turn pump down to 1 on a combi keep on 3 the whistling is prob high flow rate trying to go through small gap in rad valves try opening them more to see if quietens down
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