The room is a bathroom, well, shower.
Just to give an idea of the slope, the highest point is at corner of room ( back wall/gable end) and the joists run front to back of house. This highest joist drops around 23mm over 3m. If you go diagonal across the room, ( around 3.6m ), then the drop is around 45mm. Like I said, you don't notice it when your in room.
Talking about water, If I layed the shower tray to the slope, it would be around 8mm low, one end, it's not much is it ? And I could lay the tray level anyway.
I was more worried about water pooling in corner of room.