1. If you mean a toilet cistern:
1.1 Many manufacturers of WC inlet valves, flush valves / syphons recommend NOT using those cistern blocks. Apparently in some cases the chemicals can cause the plastic components to deteriorate.
1.2 Given regular use, limescale is unlikely to cause more of a a problem than anywhere else subject to hard water.
2. If you mean the coldwater storage cistern (big tank in loft) then:
2.1 You can't use the cistern blocks unless you want ot wash i blue water.
2.2 The only reliable way of reducing limescale is a water softener such as the Harvey / Kinetico / BWT type whic uses salt. Quite expensive to buy and expensive and disruptive (depending on existing pipework) to install. Salt isn't getting any cheaper and can be awkward to store.
2.3 You could try something like a "Combimate" or similar polyphosphate softener. These require refilling from time to time.
2.4 You can also get various "magnetic" in-line devices which claim to prevent lime scale from precipitating. I've no idea whether they work or not, but I've never seen a definitive study suggesting they do. However, they are reasonably cheap and might be worth trying.