After taking it down to get to any otherwise inaccessible parts of the electrical installation for inspection and testing, then replacing it, and also after filling in any holes cut in it for lights.
One way is to use an Undercoat first on the plasterboard, then TWO coats of GLOSS paint on the ceiling - Bathrooms tend to be damp places, and the Gloss paint holds up to moisture better than emulsion etc.
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