Right, if you have 2 ground floor WC's opposite each other as per you plan, you should be able to get away with one pipe serving both. Use a junction at the first WC, bringing the pipe from the branch up vertically to suit pan position, then continue to reach the second, coming up with a bend to meet WC position. (Imagine pipework looking like a large 'F' on its side.)
It's very unlikely either will ever block in the vertical section of drain, as long as the horizontal run can be rodded if necessary, all should be ok.
It's very unlikely either will ever block in the vertical section of drain, as long as the horizontal run can be rodded if necessary, all should be ok.