Well, in extremis you could argue you don't need the final circuit MCB or fuse at all, except when the circuit is going to be overloaded, as short circuit protection could be provided further back (one big company fuse perhaps?).
Ask yourself honestly, when did you last change a final circuit fuse or reset the circuit breaker, except for a catastrophic fault?
It can happen, but it is mercifully rare. As evidenced by the safe operation of wiring in countries where the cable only needs to be rated for the fuse at the load end - a heinous crime here, but not often a problem in practice (mostly Asia and South America in case you are wondering).
However, like running without the earth, it is not dangerous in itself, but you have to understand when you are removing a safety net which you might need in case of fault.
There is a tendency here in the well fed first world to worry too much about non-real risks, and spurs are just such a non-risk.