I just find it hard to get round the idea of controlling the temperature of all rooms based on one room, in a house where I want the rooms at very different temperatures (not even throughout). I only want to heat the rooms I'm in/using.
You cannot turn the room off, where the thermostat is located, but you can turn the TRV's down in the unused rooms. Alternatively, if it's a wireless stat, you could carry it to which ever room you are in, and set the TRV in that room to maximum.
You should never turn TRV's completely off, otherwise in freezing conditions, there is the risk of pipework and radiators freezing.
I switched because I had very poor hot water flow upstairs.
I'm surprised you have more flow from a combi, than you had with stored HW - it suggests it was wrong plumbed, or you had a restriction somewhere.
