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Deleted member 105431
The easiest and most common way other than a room stat. Is a boiler flow switch As the last trv closes there is no flow so the boiler switches off as does the pump as is fitted on some suprimas, baxi solo /megaflo .
There are far more expensive and complcated ways of controlling each and every room.
hadn't I already said that;
Baxi solo he for example has a flow switch as an interlock so no roomstat reqd although I would recommend one.