Pfizer vaccine report

ellal · 24 Nov 2020

noseall said:
How much money do you reckon they'll save by curing the planet of Covid? See if you can guess how many trillions?

But in the meantime...

"People arriving in England will be soon able to reduce their quarantine period by more than half if they pay for a Covid test after five days, the transport secretary has announced.
The rules will come into force from 15 December and the tests from private firms will cost between £65 and £120."

Other countries have decided to do the same test on arrival for free ('in house'), thus bolstering the potential of money for their own economies...

So where would you go for a family trip? One in which tests will cost often more than the budget flight? Or one that you don't have to pay an extra 'tax' that goes into private pockets hand picked by coronyism?

And would you trust that corporates such as crapita would actually provide a reliable 'service'? The evidence so far doesn't bode well !

But hey, the UK isn't known as 'treasure island' amongst the corporates for no reason!

SirGalahad · 24 Nov 2020

fillyboy said:
Astrazeneca share price down 3.8%
Analysts suspect it may not get US gov approval and the 'at cost' rollout means profits are a long way off.

That may have to do with the fact that they have not released the data like Moderna and Pfizer did. Also the efficacy of the 1.5 dose was not tested in the Brazil group.

This vaccine is based on a attenuated chimpanzee virus.

IT Minion · 24 Nov 2020

SirGalahad said:
That may have to do with the fact that they have not released the data like Moderna and Pfizer did. Also the efficacy of the 1.5 dose was not tested in the Brazil group.

This vaccine is based on a attenuated chimpanzee virus.

Apparently the 1.5 dose was accidental. They decided to continue it after discovering it had been under administered and got the surprising result that it worked better.

My bet the stock price is solely down to the not-for-profit clarification. Previously they'd had wording that said they might start charging higher rate to include a profit by July, which they've now said they won't. This dangerous display of humanity does not please investors at all.

SirGalahad · 24 Nov 2020

IT Minion said:
Apparently the 1.5 dose was accidental. They decided to continue it after discovering it had been under administered and got the surprising result that it worked better.

My bet the stock price is solely down to the not-for-profit clarification. Previously they'd had wording that said they might start charging higher rate to include a profit by July, which they've now said they won't. This dangerous display of humanity does not please investors at all.

This pretty well sums it up.

https://www.theguardian.com/busines...fficacy-findings-for-covid-19-vaccine-results

I don't think the not for profit issue is a major one. As I mentioend above - they need more data on the trial - Astra was done on 12k whilst Pfizer on 45k If I recall correctly.

In either case the vaccine is not important to AstraZ business.

JohnD · 24 Nov 2020

fillyboy said:
Astrazeneca share price down 3.8%
Analysts suspect it may not get US gov approval and the 'at cost' rollout means profits are a long way off.

Pharmaceutical share prices have been bouncing around due to ignorance, speculation and rumour.

Does this week look any less stable than any other?

(the blue one is GlaxoSK)

meanwhile, makers of rubber gloves, facemasks and other PPE have seen a share price setback.

SirGalahad · 24 Nov 2020

JohnD said:
Pharmaceutical share prices have been bouncing around due to ignorance, speculation and rumour.

Does this week look any less stable than any other?

View attachment 212579
(the blue one is GlaxoSK)

meanwhile, makers of rubber gloves, facemasks and other PPE have seen a share price setback.

The issue is that we need full data as the way they performed the trials is different.

AstraZeneca-Oxford measured their results in a different way from their two major competitors. The Moderna and Pfizer/BioNTech trials only captured Covid-19 infections in their trial pool that advanced far enough to produce symptoms, while the AstraZeneca trials conducted weekly swab tests among their participants, allowing them to detect much less severe cases — including potential asymptomatic infections — among their volunteers. These differences make it trickier to draw apples-to-apples comparisons of the efficacy of the different vaccines.

SirGalahad · 24 Nov 2020

Good read.

https://edition.cnn.com/2020/11/23/health/astrazeneca-vaccine-data-questions/index.html

ajohn · 24 Nov 2020

ellal said:
Other countries have decided to do the same test on arrival for free ('in house'), thus bolstering the potential of money for their own economies...

The problem with just testing and no iolation period first is a very strong possibility that some with it will test negative and wouldn't several days after the test. That applies to the sensitivity of the hospital type swab test as well.

It's also been tried in the far east and dropped.

ajohn · 24 Nov 2020

IT Minion said:
Apparently the 1.5 dose was accidental.

Probably hard to be sure about that as shot and a booster isn't that unusual and I can't recollect any one mentioning differences until this cropped up. It seems to be down to the immune systems behaviour. Guessing but with one dose the "phase 1" response does it's thing too quickly and T cells take longer.

IT Minion · 24 Nov 2020

ajohn said:
Probably hard to be sure about that as shot and a booster isn't that unusual and I can't recollect any one mentioning differences until this cropped up. It seems to be down to the immune systems behaviour. Guessing but with one dose the "phase 1" response does it's thing too quickly and T cells take longer.

No, they said it was an accident. The plan was two full doses

ajohn · 24 Nov 2020

This seems to be something that people wont want to experience.
https://www.mayoclinic.org/diseases-conditions/transverse-myelitis/symptoms-causes/syc-20354726

Dose changed after a couple of people had problems? Hopefully a conspiracy theory and nothing else.

IT Minion · 24 Nov 2020

ajohn said:
This seems to be something that people wont want to experience.
https://www.mayoclinic.org/diseases-conditions/transverse-myelitis/symptoms-causes/syc-20354726

Dose changed after a couple of people had problems? Hopefully a conspiracy theory and nothing else.

Nothing to do with that at all. So just a conspiracy theory.

ajohn · 24 Nov 2020

EFLImpudence said:
The first lockdown was introduced to "flatten the curve" to save The Health Service to the detriment of other illnesses.

No it was introduced to prevent the NHS from running out of capacity. It just about did that and with an accuracy that is pretty spectacular.

Now the NHS is to do other work as well so the capacity available for covid is a fair bit less so a shorter lock down followed by a game of snakes and ladders.

Going up the snakes in this case as there are no prizes for being at level 3.

Better to fall down the ladders.

Previous trends suggest all will end up at level 3 again but maybe not now that some areas that saw slower spread before the 1st lockdown have now experienced what happen when lots are carrying it and people mix.

Vinty · 24 Nov 2020

Pfizer has form for bribery and corruption.
They also have extensive interests in China.
They were also losing money until they devoloped this vaccine.
One theory is that pfizer devoloped the virus and vaccine at the same time.
They immunised all those involved in the conspiracy and then released the virus in China.
China was chosen becaused no one believes anything the Chinese say, millions of people in the West have watched the film Dr No, so they know what the Chinese are capable of.
Meanwhile back at pfizer some evil twunt sits in a chair stroking his white cat watching pfizers share price go through the roof.
Of course all of the above could be a load of cobblers but these days, who really knows.

Trazor · 24 Nov 2020

Vinty said:
Pfizer has form for bribery and corruption.
They also have extensive interests in China.
They were also losing money until they devoloped this vaccine.
One theory is that pfizer devoloped the virus and vaccine at the same time.
They immunised all those involved in the conspiracy and then released the virus in China.
China was chosen becaused no one believes anything the Chinese say, millions of people in the West have watched the film Dr No, so they know what the Chinese are capable of.
Meanwhile back at pfizer some evil twunt sits in a chair stroking his white cat watching pfizers share price go through the roof.
Of course all of the above could be a load of cobblers but these days, who really knows.

Why then would the CEO of Pfizer, sell $5.6million of his own shares on the day of the announcement.

Pfizer vaccine report

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